A few years ago, I helped a small distributor source toothpaste for their new product line. The first factory shipped late, the second changed formulas without notice, and the third finally got it right after months of back-and-forth.
That long process taught me that finding a reliable toothpaste manufacturer isn’t about luck, it’s about knowing who actually delivers consistent results.
You can trust this review because it’s based on real supplier communication, product sampling, and client feedback from companies that manufacture and distribute oral care products.
In this article, you’ll see nine toothpaste manufacturers that businesses can depend on for steady supply, safe ingredients, and professional service. By the end, you’ll know which ones match your company’s production goals.
Finding a supplier that keeps promises shouldn’t be a gamble.
So, let’s get started!
Quick Comparison Chart
Before we explore each company in depth, here’s a quick side-by-side view of the nine manufacturers. This table gives you a snapshot of their focus areas, strengths, and positioning so you can compare at a glance.
| Manufacturer | Best For | Location | Established | Pricing | Certifications | Not Ideal For |
| Lider Care | Private label toothpaste | Istanbul, Turkey | 1999 | Mid-range | ISO 9001, ISO 22716, Halal | Brands needing high-tech whitening |
| Lion Corporation | Fluoride & enzyme R&D | Tokyo, Japan | 1891 | Mid–Premium | ISO 9001, ISO 14001, GMP | Small private label startups |
| TY Cosmetic | Full-service cosmetics OEM | Guangzhou, China | 2009 | Mid-range | GMP, EU/FDA Compliant | Oral-care only manufacturers |
| Procter & Gamble (P&G) | Global oral care leader | Cincinnati, USA | 1837 | Mid–Premium | ISO 9001, ISO 14001, ADA | Small-scale or niche brands |
| Haleon | Medically backed formulas | Weybridge, UK | 2022 | Premium | ISO 13485, GMP, ADA | Natural or lifestyle brands |
| Sunstar Group | Preventive oral care | Etoy, Switzerland | 1932 | Mid–Premium | ISO 9001, ISO 13485, GMP | Low-cost or mass production |
| Marvis | Luxury toothpaste design | Florence, Italy | 1958 | Premium | GMP | Clinical or value markets |
| Cinoll | OEM oral care products | Shenzhen, China | 2011 | Mid-range | ISO 9001, ISO 22716, FDA | Premium or luxury brands |
| Boka | Natural fluoride-free care | Boulder, USA | 2016 | Mid–Premium | GMP, Vegan, Cruelty-Free | Large-scale fluoride producers |
With this overview in mind, we’ll now dive into each manufacturer’s details to see which best fits your company’s goals.
1. Lider Care | Best for Private Label Toothpaste Manufacturing
Lider Care is a Turkish-based manufacturer working closely with distributors and private label brands to create complete toothpaste solutions. They specialize in flexible batch runs, customized packaging, and market-ready formulations. If your business wants to expand its toothpaste line without heavy upfront investment, Lider Care offers the reliability and compliance support to make that happen.
- Established Date: 1999
- Location: Istanbul, Turkey
- Reach: Exports to more than 30 countries across Europe, the Middle East, and North Africa
- Positioning: Full-service OEM and private label manufacturer for oral, hair, and personal care products
- Pricing Level: Mid-range
- Certifications: ISO 9001, ISO 22716 (GMP), and Halal Certified
Product Range
- Whitening Formulas: Offers fluoride and non-fluoride variants developed for brightening and stain removal. These allow your brand to provide effective whitening while maintaining gentle care for daily users.
- Kids’ and Family Lines: Produces mild, safe formulations with fruit or mint flavors approved for children. You can target family-focused markets with products that meet strict safety and labeling requirements.
- Herbal and Natural Variants: Provides toothpaste with plant extracts like mint, clove, and charcoal. These options help your brand tap into the growing demand for natural and eco-conscious oral care.
- Medicated and Functional Toothpaste: Creates formulas for sensitivity, gum health, and enamel protection. This lets your business compete in specialized segments requiring clinically backed results.
Research and Development
- Flexible OEM Production: Handles both small and large batch orders with adaptable production lines. This flexibility helps you manage seasonal demand and market testing efficiently.
- In-House R&D Laboratory: Develops custom flavors, textures, and packaging aligned with your brand goals. Their R&D support helps you differentiate your products in competitive retail spaces.
- Regulatory and Quality Assurance: Complies with EU Cosmetic Regulation and holds ISO 9001 and GMP certifications. This gives your company confidence in consistent quality and safe production.
Takeaway
Lider Care is an excellent partner if your company needs reliable private label toothpaste manufacturing with flexible productiont. However, if your brand focuses on advanced whitening technologies, you may find their capabilities more suitable for mid-tier expansion than mass-market manufacturing.
2. Lion | Best for Fluoride and Enzyme-Based Toothpaste Innovation
Lion Corporation is one of Japan’s longest-standing oral care manufacturers with deep expertise in fluoride and enzyme-based toothpaste formulations. The company serves both global brands and dental professionals by offering scientifically tested products for cavity prevention and gum care. If your business values proven R&D , Lion Corporation provides the research foundation and credibility to support your product line.
- Established Date: 1891
- Location: Tokyo, Japan
- Reach: Operates in over 30 countries, with strong presence in Asia and growing reach in North America
- Positioning: Manufacturer of oral, household, and health care products supported by advanced R&D and safety testing
- Pricing Level: Mid to Premium
- Certifications: ISO 9001, ISO 14001, and GMP Certified
Product Range
- Fluoride Toothpaste: Features fluoride formulations designed to strengthen enamel and protect against cavities. These options help your brand offer clinically proven protection that meets modern oral care standards.
- Enzyme-Based Toothpaste: Combines natural enzymes with mild surfactants to remove plaque gently. This lets your business introduce innovative, low-foam formulas appealing to sensitive-care markets.
- Gum Care Toothpaste: Includes active ingredients like IPMP and vitamin E to maintain gum health. These products let your brand position itself in preventive dental care segments with real efficacy claims.
- Children’s Toothpaste: Offers mild flavors and safe fluoride levels suitable for young users. This helps your company build trust with parents and healthcare professionals alike.
Research and Development
- Advanced Oral Health Studies: Lion’s R&D teams conduct in-depth studies on plaque formation and tooth mineralization. This research supports your product’s credibility with data-driven formulations backed by decades of expertise.
- Global Quality Control Centers: Operates multiple laboratories for ingredient testing and product safety validation. This infrastructure allows your business to confidently sell products that meet regional regulatory standards.
- Innovative Packaging Technology: Develops moisture-resistant tubes and precision caps that extend product shelf life. This helps your brand reduce waste and maintain customer satisfaction with consistent texture and usability.
Takeaway
Lion Corporation is ideal if your company wants reliable, science-backed toothpaste production supported by extensive R&D and regulatory credibility. However, if your brand needs smaller custom runs or unconventional natural formulations, you may find their system better suited for established, research-driven product lines.
3. TY Cosmetic | Best for Full-Service Private Label Cosmetics
TY Cosmetic is a large-scale Chinese manufacturer specializing in OEM and ODM production for skincare, haircare, and personal care products. The company operates a 30,000 m² facility with 68 production lines and exports to more than 70 countries worldwide. If your business wants to create or expand a cosmetic brand with complete production support, TY Cosmetic offers the infrastructure and flexibility to make that possible.
- Established Date: 2009
- Location: Guangzhou, China
- Reach: Serves more than 2,000 brand clients globally
- Positioning: Full-service manufacturer for skincare, haircare, body care, and men’s grooming
- Pricing Level: Mid-range
- Certifications: GMP Certified and compliant with EU and FDA manufacturing standards
Product Range
- Skincare Products: Offers creams, serums, toners, and facial masks formulated for different skin types and concerns. This allows your brand to build a complete skincare collection with options for brightening, anti-aging, or hydration.
- Haircare and Body Care: Produces shampoos, conditioners, lotions, and body washes with various textures and scents. These lines give your business the ability to cater to both daily care and premium treatment markets.
- Men’s Grooming and Baby Care: Develops 2-in-1 cleansing products for men and gentle, dermatologist-tested creams for babies. This product range helps your brand reach two growing markets with distinct formulation needs.
- Private Label Sets and Kits: Provides customizable kits and complete product lines ready for branding and packaging. This service helps you launch faster and maintain consistent quality across all product categories.
Research and Development
- Formulation Development: Maintains a team of chemists and product engineers who create custom textures and fragrances. This lets your company introduce distinctive formulations aligned with your branding and target audience.
- Material and Quality Testing: Runs internal testing on stability, safety, and performance before products reach production. This process gives your business confidence that every batch meets both quality and regulatory expectations.
- Trend-Focused Innovation: Continuously studies global cosmetic trends to refresh and expand its formula library. This approach helps your brand stay current with emerging market preferences and ingredient innovations.
Takeaway
TY Cosmetic is a dependable choice for brands seeking a full-service manufacturer with strong R&D, packaging flexibility, and global export experience. However, if your business focuses solely on oral care or, their capabilities may not suit your needs.
4. Procter & Gamble (P&G) | Best for Global Brand-Scale Oral Care Solutions
Procter & Gamble is one of the largest consumer goods manufacturers, known for producing globally recognized toothpaste brands like Crest and Oral-B. Their strength lies in consistent performance, large-scale production, and advanced dental science integration. If your business requires mass-market reliability and access to proven oral care technology, P&G provides unmatched expertise and infrastructure.
- Established Date: 1837
- Location: Cincinnati, Ohio, USA
- Reach: Over 180 countries worldwide
- Positioning: Global manufacturer of oral care, personal care, and household products
- Pricing Level: Mid to Premium
- Certifications: ISO 9001, ISO 14001, GMP, and ADA Certified Products
Product Range
- Whitening Systems: Offers professional-grade whitening products with hydrogen peroxide and enamel-safe technology. This lets your company provide consumers with visibly effective results supported by clinical research.
- Cavity Protection Toothpaste: Features fluoride-rich formulas that strengthen enamel and fight decay. These formulations allow your business to serve mainstream markets confidently with consistent performance.
- Sensitivity Relief Lines: Produces toothpaste with potassium nitrate and stannous fluoride for gentle desensitization. This helps your brand build trust among users with recurring sensitivity issues.
- Kids’ Oral Care: Includes gentle, fun-flavored options featuring popular characters. These products allow your company to expand into family-oriented retail spaces easily.
Research and Development
- Dedicated Dental Research Centers: Runs research hubs focused on fluoride science and biofilm reduction. These facilities support your business with clinically validated claims and ingredient transparency.
- Data-Driven Product Testing: Uses global consumer feedback and lab trials to refine every formulation. This helps your company release products proven to perform well under real-world conditions.
- Packaging Efficiency Programs: Invests in lightweight and recyclable packaging innovations. This enables your brand to align with global sustainability goals while maintaining product safety.
Takeaway
P&G is a trusted choice for companies seeking large-scale, research-backed oral care production and brand recognition. However, if your business requires smaller, custom formulations or private label flexibility, P&G’s corporate scale may not match niche manufacturing needs.
5. Haleon | Best for Medically Backed Toothpaste Manufacturing
Haleon, formerly part of GSK, is a health-focused company known for producing Sensodyne and Parodontax. They specialize in medically tested toothpaste designed for sensitive teeth and gum health. If your business serves dental clinics or pharmacy chains, Haleon provides clinically validated products trusted by professionals.
- Established Date: 2022
- Location: Weybridge, United Kingdom
- Reach: Global distribution across more than 100 markets
- Positioning: Healthcare manufacturer specializing in oral care, pain relief, and wellness products
- Pricing Level: Premium
- Certifications: ISO 13485, GMP, and ADA Approved
Product Range
- Sensitivity Toothpaste: Formulated with potassium nitrate and stannous fluoride for lasting relief. This allows your brand to market proven sensitive-care products that deliver real comfort benefits.
- Gum Health Lines: Features antibacterial and anti-inflammatory properties that promote gum healing. This product type helps your business appeal to clinical and therapeutic oral care buyers.
- Whitening and Repair Variants: Combines gentle abrasives and fluoride to whiten while repairing enamel. These formulations let your brand offer balanced solutions without harsh effects.
- Children’s Oral Care: Produces low-fluoride and fluoride-free versions for younger users. This segment enables you to cover the complete oral care portfolio under one supplier.
Research and Development
- Clinical Trial Integration: Conducts human trials to validate claims for sensitivity and enamel repair. This scientific backing helps your brand maintain credibility with professional partners.
- Health Science Collaboration: Works with dental experts and universities to refine active ingredients. This collaboration gives your business access to medically verified formulations trusted by the healthcare community.
- Safety and Compliance Testing: Maintains strict regulatory compliance for all global markets. This helps your brand avoid setbacks during registration and export processes.
Takeaway
Haleon is a strong partner for brands entering the clinical or dental supply market where scientific proof and safety standards are top priorities. However, if your focus is lifestyle-driven oral care or natural formulations, their product lines may feel more clinical than consumer-oriented.
6. Sunstar | Best for Preventive Oral Care and Dental Partnerships
Sunstar is a Japanese-Swiss manufacturer recognized for integrating dental science with consumer oral care solutions. The company collaborates with dentists and universities to develop toothpaste lines under its GUM and Ora2 brands. If your business values clinical credibility and preventive care innovation, Sunstar offers proven expertise and manufacturing dependability.
- Established Date: 1932
- Location: Etoy, Switzerland (Headquarters)
- Reach: Operates in over 90 countries
- Positioning: Oral care and health manufacturer with strong medical collaboration
- Pricing Level: Mid to Premium
- Certifications: ISO 9001, ISO 13485, and GMP Certified
Product Range
- Plaque Control Toothpaste: Developed with antibacterial agents for daily gum care. This lets your business target consumers who prioritize oral hygiene maintenance and prevention.
- Fluoride and Enamel Care Lines: Designed to strengthen enamel and reduce demineralization. These products help your brand meet both preventive and restorative care needs.
- Whitening Variants: Uses safe abrasives and mild peroxides for gradual whitening. This allows you to serve customers seeking aesthetic results without harsh chemicals.
- Herbal and Natural Blends: Offers plant-based extracts like green tea and sage for fresh breath. This range gives your brand options to tap into natural oral care markets.
Research and Development
- Collaborative Dental Research: Partners with dental schools and professionals to refine preventive formulas. This collaboration strengthens your product’s credibility among health-conscious consumers.
- Ingredient Safety Validation: Tests all ingredients through clinical and laboratory assessments. This ensures your company delivers products that meet international safety expectations.
- Product Innovation Centers: Operates research facilities in Japan and Europe focused on oral microbiome studies. This gives your business access to forward-looking, evidence-based formulations.
Takeaway
Sunstar is an excellent partner if your company targets preventive oral care supported by clinical validation and long-term reliability. However, if your focus is low-cost production or purely cosmetic toothpaste lines, their science-driven approach may exceed your immediate manufacturing needs.
7. Marvis | Best for Luxury and Designer Toothpaste Branding
Marvis is an Italian toothpaste brand known for turning oral care into a luxury experience. The company blends traditional Italian craftsmanship with modern flavor innovation to create products that appeal to lifestyle-driven consumers. If your business targets premium retail or hotel amenities markets, Marvis offers the sophistication and packaging appeal to elevate your product lineup.
- Established Date: 1958
- Location: Florence, Italy
- Reach: Distributed in over 60 countries through luxury retailers and hospitality partners
- Positioning: Premium toothpaste manufacturer focused on sensory experience and visual branding
- Pricing Level: Premium
- Certifications: GMP Certified
Product Range
- Classic Toothpaste Collection: Features flavors such as mint, jasmine, and licorice that deliver a refined brushing experience. This allows your business to attract consumers who value both function and sensory pleasure in oral care.
- Whitening and Sensitive Lines: Combines gentle whitening agents with soothing ingredients for daily comfort. These options help your brand serve customers who want premium quality with real performance benefits.
- Limited Edition Flavors: Releases creative seasonal and travel-inspired collections that stand out on retail shelves. This flexibility gives your brand opportunities to refresh its offerings and keep customers engaged.
- Mini and Gift Sets: Provides compact versions and curated boxes ideal for hotels, boutiques, and gifting. These formats let your company expand into hospitality and retail display markets effortlessly.
Research and Development
- Flavor Innovation Team: Develops complex flavor blends that combine freshness with gourmet profiles. This enables your brand to deliver a unique product experience that feels both luxurious and memorable.
- Packaging Design Studio: Crafts visually appealing tubes and boxes with distinctive Italian style. This creative focus allows your business to strengthen brand perception and appeal to design-conscious customers.
- Quality and Safety Control: Maintains consistent testing to ensure product texture, taste, and hygiene meet international standards. This gives your company reliable quality in every shipment, supporting brand trust and customer satisfaction.
Takeaway
Marvis is an ideal choice if your business aims to offer high-end toothpaste that doubles as a lifestyle product with visual and sensory appeal. However, if your focus is clinical oral care or cost-sensitive distribution, their luxury positioning may not align with your target market.
8. Cinoll | Best for OEM Toothpaste and Oral Care Product Manufacturing
Cinoll is a Chinese manufacturer specializing in OEM and ODM production of toothpaste, toothbrushes, and oral care accessories. They combine in-house formulation with large-scale packaging capabilities, making them suitable for brands seeking private label or customized solutions. If your company needs reliable manufacturing support with flexible order quantities, Cinoll delivers practical and compliant production options.
- Established Date: 2011
- Location: Shenzhen, China
- Reach: Serves global distributors and private label brands across Asia, Europe, and North America
- Positioning: OEM/ODM manufacturer focused on complete oral care product lines
- Pricing Level: Mid-range
- Certifications: ISO 9001, ISO 22716 (GMP), FDA Registered
Product Range
- Whitening Toothpaste: Produces formulations using fluoride and mild whitening ingredients suitable for daily use. This helps your business meet mainstream consumer demand for safe, visible results.
- Charcoal and Herbal Toothpaste: Creates natural-based variants using plant extracts and activated charcoal. These lines allow your brand to capture eco-conscious customers seeking clean-label alternatives.
- Kids’ and Family Toothpaste: Offers colorful packaging and gentle formulations designed for families. This range lets your business expand into child-friendly and household-oriented retail markets.
- Toothbrushes and Accessories: Manufactures electric and manual toothbrushes, interdental tools, and dental floss. This enables your company to offer complete oral care kits from a single supplier.
Research and Development
- Custom Product Development: Provides R&D support for new flavor creation, texture adjustment, and packaging design. This helps your company build brand identity through products tailored to your specifications.
- Material and Ingredient Testing: Conducts in-house safety and performance testing for all ingredients and packaging materials. This ensures your business receives consistent quality that meets export regulations.
- Market Trend Research: Monitors oral care trends to suggest innovative product concepts and new formulations. This gives your brand the ability to stay relevant in competitive consumer markets.
Takeaway
Cinoll is a strong choice if your business wants a dependable partner for OEM and ODM toothpaste production backed by strong compliance and R&D support. However, if your brand focuses on luxury positioning or highly specialized clinical formulas, their production model may be more aligned with mainstream consumer products.
9. Boka | Best for Modern, Natural, and Fluoride-Free Toothpaste Solutions
Boka is an American oral care company known for developing toothpaste with hydroxyapatite, a fluoride alternative that helps strengthen enamel naturally. The company focuses on blending clean ingredients with modern branding and direct-to-consumer appeal. If your business targets health-conscious consumers or boutique retail chains, Boka provides innovative and market-tested solutions.
- Established Date: 2016
- Location: Boulder, Colorado, USA
- Reach: Distributed across North America with growing presence in online and retail markets
- Positioning: Modern oral care brand centered on natural, science-based formulations
- Pricing Level: Mid to Premium
- Certifications: GMP Certified, Vegan, and Cruelty-Free
Product Range
- Hydroxyapatite Toothpaste: Offers fluoride-free toothpaste that remineralizes enamel and reduces sensitivity. This allows your business to serve customers seeking gentle yet effective natural oral care.
- Whitening and Freshness Lines: Combines natural flavor oils and gentle abrasives for stain removal and long-lasting freshness. These products help your brand attract users looking for performance without synthetic ingredients.
- Charcoal and Herbal Options: Produces blends with activated charcoal, aloe vera, and green tea extract. This variety gives your brand versatility in expanding clean and eco-friendly product offerings.
- Kids’ Oral Care Products: Provides safe and mild formulations for children using non-toxic ingredients. This gives your company access to family-focused markets where ingredient safety is a top concern.
Research and Development
- Ingredient Transparency Program: Uses clearly sourced natural ingredients and publishes testing data for consumer trust. This approach helps your business communicate authenticity and build long-term loyalty.
- Product Testing and Clinical Validation: Conducts scientific studies to evaluate hydroxyapatite performance and safety. This data supports your brand with credible claims backed by independent research.
- Sustainable Packaging Development: Introduces recyclable tubes and environmentally conscious designs. This commitment lets your company align with sustainability values that appeal to modern consumers.
Takeaway
Boka is a great partner if your company focuses on clean, natural toothpaste backed by research and modern branding. However, if your brand requires large-scale mass production or traditional fluoride-based formulas, their niche specialization may not fully match your needs.
Conclusion
Finding the right toothpaste manufacturer took effort, but the lessons were worth it. Each company in this list brings something different, from luxury branding to science-based innovation.
You’ve now seen what reliability and flexibility look like in this industry. If your business is ready to turn these insights into action, start building your next product line with confidence.
The right partner can make all the difference for your brand. Contact TY Cosmetic for private label and full-service personal care production today!
